Salies de Béarn is situated approximately mid-way between Bayonne, on the Atlantic coast, and Pau to the east. It is only a few kilometres from the A64 motorway.
Biarritz Airport is situated about 45 minutes' drive away.
Tarbes - Lourdes Airport, to the east of Pau, is around an hours' drive.
Bordeaux Airport is around 2 hours' drive and Toulouse about 2.5 hours.
There are railway stations at nearby Puyoo and Orthez.